Solid-State Characterization and Biological Activity of Betulonic Acid Derivatives.
نویسندگان
چکیده
Betulonic acid belongs to the pentacyclic triterpenic derivative class and can be obtained through the selective oxidation of betulin. In this study we set obtaining several functionalized derivatives of this compound by its condensation with several amino compounds such as aminoguanidine, hydroxylamine, n-butylamine and thiosemicarbazide as our goal. The functionalization of the parent compound led to several molecules with antiproliferative potential, the most promising being 3-2-carbamothioylhydrazonolup-20(29)-en-28-oic acid.
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ورودعنوان ژورنال:
- Molecules
دوره 20 12 شماره
صفحات -
تاریخ انتشار 2015